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Perry G. Rigby, MD; Peyton T. Pratt, MD; Robert C. Rosenlof, MD; Henry M. Lemon, MD

Arch Intern Med. 1968;121(1):67-70.

Abstract
Thirty-nine multiple family cases have been recorded with 77 pairs and 91 involved relatives having leukemia or lymphoma. Thirty-two of the 39 families involved a close genetic relationship between affected siblings or parent-child pairs. The multiple family case members died earlier than single family case members on a comparative study. This suggests that genetic factors are of importance in the etiology of these malignant hematologic proliferations.

Author Affiliations
Omaha

From the Eppley Institute and the Department of Internal Medicine, University of Nebraska College of Medicine, Omaha.

Footnotes
Received for publication June 14, 1967; accepted Sept 11.

Reprint requests to Eugene C. Eppley Institute for Research in Cancer and Allied Diseases, 42nd and Dewey Ave, Omaha 68105 (Dr. Rigby).

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