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Submaxillary Potassium Concentration in True and Pseudoprimary Aldosteronism
Stephen Wotman, DDS;
Leslie Baer, MD;
Irwin D. Mandel, DDS;
John H. Laragh, MD
Arch Intern Med. 1970;126(2):248-251.
Abstract
Preoperative electrolyte concentrations in parotid and submaxillary saliva were compared retrospectively from patients with true and pseudoprimary aldosteronism as well as patients with essential hypertension and normal subjects. Patients with primary aldosteronism due to an adrenal adenoma uniformly exhibited an increased potassium concentration in their submaxillary gland secretion. The range of values exhibited by these patients did not overlap with the consistently normal values observed in patients with essential hypertension and also in patients with pseudoprimary aldosteronism (associated with adrenal hyperplasia). This measurement may, therefore, be useful in identifying patients with primary aldosteronism and in separating them preoperatively from the clinically similar entity of pseudoprimary aldosteronism.
Author Affiliations
New York
From the Division of Preventive Dentistry and Community Health, School of Dental and Oral Surgery, Department of Medicine, College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, New York. Dr. Mandel is the recipient of a career scientist award of the Health Research Council of the City of New York, contract 1-636.
Footnotes
Received for publication March 11, 1970; accepted May 11.
Reprint requests to 630 W 168th St, New York 10032 (Dr. Wotman).
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