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Hypopituitarism Due to Localized Hypothalamic Lesions
Salman D. Gailani, MB;
Augustine L. Roque, MD;
Pierre Band, MD;
Charles Ross, MD
Arch Intern Med. 1970;126(2):284-286.
Abstract
A 59-year-old man with inoperable bronchogenic carcinoma manifested diabetes insipidus and progressive impairment of adenohypophyseal function. Postmortem examination revealed bilaterally symmetrical localized hemorrhagic hypothalamic lesions while the adenohypophysis was virtually intact. This observation confirms findings from animal experiments and clinical impressions which indicate control of the adenohypophyseal function by the hypothalamus.
Author Affiliations
Buffalo
From the departments of medicine A (Drs. Gailani and Band), pathology (Dr. Roque), and thoracic surgery (Dr. Ross), Roswell Park Memorial Institute, Buffalo. Dr. Roque is now with; the Cauteret Hospital, Morehead City, NC. Dr. Band is now with the University of Alberta, Edmonton. Dr. Ross is now with the Perth Amboy (NJ) General Hospital.
Footnotes
Received for publication June 19, 1969; accepted Aug 6.
Reprint requests to 666 Elm St, Buffalo 14203 (Dr. Gailani).
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ABSTRACT
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