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Ciliary Motility Studies
Tore Dalhamn, MD
Arch Intern Med. 1970;126(3):424-427.
Abstract
For measurement of ciliary activity and toxic inhalation effects it is necessary to take at least the following into consideration. Comparable effects on human beings are the primary concern. Concerning choice of animal, it is doubtful whether or not results from lower species (mussels, oysters) can be directly applied to vertebrates. Few reports in which in vivo or in vitro experiments can be compared have been published. Concerning the ciliary activity and effects upon the same, there are some indications for obtaining the same results with in vivo or in vitro preparations from the same species. Observation techniques are all very similar with observation through a microscope with vertical light. For choice of registration techniques three methods are available; filming, stroboscopy, or photoelectric cell. At present, for in vivo preparations the filming is superior.
Author Affiliations
Uppsala, Sweden
From the Institute of Hygiene, Uppsala University, Uppsala, Sweden.
Footnotes
Received for publication Dec 22, 1969; accepted March 16,1970.
Read before the session entitled Mucociliary Responses (William M. Thurlbeck, MB, ChB, chairman) of the workshop on Pulmonary Responses to Inhaled Materials: An Evaluation of Model Systems, Castle Harbour, Bermuda, Oct 23,1969.
Reprint requests to Institute of Hygiene, University of Uppsala, Box 17007, S-104 62, Stockholm 17 (Dr. Dalhamn).
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