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Charles B. Carrington, MD; Thomas J. Green, MD

Arch Intern Med. 1970;126(3):464-465.

Abstract
It is conceivable that preoccupation with the granular pneumocyte's role in the reactions to alveolar injury is premature; perhaps it is even irrelevant. However, there is sufficient evidence to justify at least some additional probing into the possibility that this cell has an important reparative function unrelated to surfactant synthesis. A better understanding of this function may also contribute to clarification of the relationships between organizing interstitial pneumonia and such reactions as desquamative interstitial pneumonia and pulmonary alveolar proteinosis in which the granular pneumocyte is especially prominent.

Author Affiliations
La Jolla, Calif

From the Department of Pathology, University of California at San Diego, La Jolla.

Footnotes
Received for publication Dec 22, 1969; accepted March 2,1970.

Read before the session entitled Alveolar Responses (Joseph D. Brain, ScD, chairman) of the workshop on Pulmonary Responses to Inhaled Materials: An Evaluation of Model Systems, Castle Harbour, Bermuda, Oct 24,1969.

Reprint requests to 310 Cedar St, New Haven, Conn 06510 (Dr. Carrington).

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