This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Ragnar Rylander, MD

Arch Intern Med. 1970;126(3):496-499.

Abstract
Experimental models are used to study the defense of the lung to infectious agents. The various lung defense mechanisms are chiefly the mechanical clearance brought about by the mucus transport and bronchial clearance brought about by pulmonary macrophages. From the effects on these mechanisms after exposure to environmental agents it is concluded that a deficiency in either of the mechanisms will lead to conditions favorable for the development of disease. The experimental models used for the study of the defense mechanisms are discussed in view of their functional importance and possible changes present after exposure to environmental agents.

Author Affiliations
Stockholm

From the Department of Environmental Hygiene, Karolinska Institute, and National Institute of Public Health, Stockholm.

Footnotes
Received for publication Dec 22, 1969; accepted March 2,1970.

Read before the session entitled Integration of Responses and Model Systems (Peter T.

Macklem, PhD, chairman ) of the workshop on Pulmonary Responses to Inhaled Materials: An Evaluation of Model Systems, Castle Harbour, Bermuda, Oct 24, 1969.

Reprint requests to Department of Environmental Hygiene, National Institute of Public Health, 10401 Stockholm 60 (Dr. Rylander).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?