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Rolf F. Barth, MD; James T. Willerson, MD; L. Maximilian Buja, MD; John L. Decker, MD; William C. Roberts, MD

Arch Intern Med. 1970;126(4):627-630.

Abstract
A patient had primary systemic amyloidosis with severe cardiac involvement and IgG paraproteinemia. Numerous intramural coronary arteries were occluded by amyloid deposits, but arteriosclerosis of the extramural arteries was absent. The amyloid coronary artery disease was associated with angina pectoris, a myocardial infarct, and mural thrombi which resulted in cerebral, renal, pulmonic, and coronary arterial emboli.

Author Affiliations
Bethesda, Md

From the Pathologic Anatomy Branch, National Cancer Institute (Dr. Barth), the Arthritis and Rheumatism Branch, National Institute of Arthritis and Metabolic Diseases (Drs. Willerson and Decker), and the Section of Pathology, National Heart and Lung Institute (Drs. Buja and Roberts), Bethesda, Md. Dr. Barth is now with the University of Kansas Medical Center, Kansas City, and Dr. Willerson is now with the Massachusetts General Hospital, Boston.

Footnotes
Received for publication March 16, 1970; accepted June 3.

Reprint requests to the Department of Pathology and Oncology, University of Kansas Medical Center, 39th St and Rainbow Blvd, Kansas City, Kan 66103 (Dr. Barth).

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