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Effect of Postural Stimulation

Tatiana A. Assaykeen, PhD; Ronald A. Castellino, MD; Thomas A. Love, MD; Thomas A. Stamey, MD

Arch Intern Med. 1971;128(3):378-379.

Abstract
The response to upright posture, measured by changes in renin activity in renal (RVR) and peripheral (PVR) veins was studied in eight normotensive, healthy adults on a normal sodium intake. Measurements were made while the subjects were supine and after 15 and 30 minutes upright. The RVR increased from a mean of 236 ± 82 ng/100 ml to 530 ± 170 ng/100 ml and 655 ± 217 ng/100 ml, 15 and 30 minutes after the subjects assumed the upright posture (P < 0.05). During the same interval, PVR increased in proportion to the renal venous changes. These data provide control values in healthy human adults for simultaneous RVR and PVR measured by the Boucher method.

Author Affiliations
Stanford, Calif

From Stanford University School of Medicine, Stanford, Calif. Dr. Love is now with Chelsea Naval Hospital, Boston.

Footnotes
Received for publication Nov 16, 1970; accepted Feb 25, 1971.

Reprint requests to Department of Surgery, Division of Urology, Stanford University School of Medicine, Stanford, Calif 94305 (Dr. Assaykeen).

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