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Endocarditis Due to Micrococci and Staphylococcus epidermidis
Thomas F. Keys, MD;
William L. Hewitt, MD
Arch Intern Med. 1973;132(2):216-220.
Abstract
Endocarditis due to micrococci and staphylococci other than Staphylococcus aureus has increased with modern cardiovascular surgery. From 1956 to 1971, Micrococcus species and S epidermidis caused 19 instances of endocarditis at the University of California at Los Angeles, accounting for 12% of all such instances. Cardiac surgery had been performed from several days to six months previously on nine patients. All had received antibiotic prophylaxis during surgery. Most of the causative organisms were resistant to penicillin G. Treatment resulted in four cures, three relapses, and two deaths. In the ten patients who had not had recent cardiac surgery, endocarditis followed urologic procedures in three patients and cardiac catheterization and dental prophylaxis in one patient each. In six patients, the causative organism was sensitive to penicillin G. In contrast to the surgical group, all but one patient were cured of endocarditis.
Author Affiliations
Los Angeles
From the Department of Medicine, Division of Infectious Diseases, University of California at Los Angeles. Dr. Keys is now at the Veterans Administration Hospital, Sepulveda, Calif.
Footnotes
Received for publication April 24, 1972; accepted Aug 31.
Read in part at the 11th Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlantic City, NJ, Oct 22, 1971.
Reprint requests to Division of Infectious Diseases, Center for the Health Sciences, UCLA, Los Angeles 90024 (Dr. Hewitt).
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