This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Acute Hypercalcemia During Acute Renal Failure

Bruce S. Chertow, MD; MAJ Stephen R. Plymate, MC; Frank O. Becker, MD

Arch Intern Med. 1974;133(5):838-840.

Abstract
A patient with idiopathic hypoparathyroidism was resistant to the usual doses of ergocalciferol. She developed acute renal failure as a consequence of ureteral ligation with secondary renal parenchymal inflammation, and hypercalcemia was noted during the diuretic phase of renal failure. On complete recovery from that renal failure, she became sensitive to doses of ergocalciferol that had previously been ineffective.

The occurrence of hypercalcemia in this patient with hypoparathyroidism suggests that the hypercalcemia of acute renal failure may not necessarily be dependent on parathyroid hormone, and in some cases may be related to alterations in vitamin D metabolism or end-organ responsiveness.

Author Affiliations
Chicago; USA, Tacoma, Wash; Chicago

From the Endocrinology Section and Department of Medicine, VA West Side Hospital, and University of Illinois College of Medicine, Chicago (Dr. Chertow); Endocrine Service, Department of Medicine, Madigan General Hospital, Tacoma, Wash (Dr. Plymate); and the Section of Endocrinology, Department of Medicine, Rush Presbyterian St. Luke's Medical Center, Chicago (Dr. Becker).

Footnotes
Received for publication Jan 19,1973; accepted June 11.

Reprint requests to Endocrinology Section (MP 172), VA West Side Hospital, PO Box 8195, Chicago 60680 (Dr. Chertow).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?