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Immunochemical, Clinical, and Pathological Features of  -Chain Disease
Maxime Seligmann, MD
Arch Intern Med. 1975;135(1):78-82.
Abstract
Making the diagnosis of  -chain disease in the laboratory is difficult. Immunologic and structural characteristics of the abnormal protein were shown in results of cellular studies. There are clinicopathological features associated with the protein abnormality. The peculiar geographic origin of patients affected with -chain disease and the possible reversibility of the hyperplastic process at its early stage lead to some considerations of cause.
Author Affiliations
From the Research Institute of Blood Diseases, University of Paris VII, Hôpital Saint-Louis, Paris.
Footnotes
Received for publication March 7, 1974; accepted May 16.
Read before the Symposium on Myeloma, Atlanta, Oct 22, 1973.
Reprint requests to Hôpital Saint-Louis, 2, place du Dr. Fournier, 75475 Paris Cedex 10, France (Dr. Seligmann).
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