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Complications in Insulin-Dependent Patients Accepted for Renal Transplantation

Jeffrey R. Shideman; Theodore J. Buselmeier, MD; Carl M. Kjellstrand, MD

Arch Intern Med. 1976;136(10):1126-1130.

Abstract
The hemodialysis complications in 67 insulin-dependent diabetic patients accepted for renal transplantation were compared with those in 67 nondiabetic hemodialysis patients. Eleven of the 67 diabetic patients died before receiving a renal transplant—four of myocardial infarction, three of dialysis-related causes, and four of infections. One of the 67 nondiabetic patients died of infection before transplantation. The diabetic patients experienced more complications on dialysis than did the nondiabetic patients; they were more hypertensive and required more ultrafiltration during dialysis. In addition, the diabetic patients had a higher incidence of hypertensive episodes during dialysis, as well as a high incidence of predialysis hyperglycemia. These findings suggest that diabetic patients with renal failure should be dialyzed more frequently and transplanted as soon as possible in order to decrease the complications associated with hemodialysis.

(Arch Intern Med 136:1126-1130, 1976)

Author Affiliations
From the Division of Nephrology, departments of medicine and surgery, University of Minnesota Hospitals, Minneapolis.

Footnotes
Received for publication March 11, 1976; accepted March 22.

Reprint requests to Box 485, University of Minnesota Hospitals, Minneapolis, MN 55455 (Dr Kjellstrand).

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