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Staphylococcal Sepsis in Patients on Chronic Hemodialysis RegimensIntravenous Treatment With Vancomycin Given Once Weekly
Camilo G. Barcenas, MD;
Thomas J. Fuller, MD;
Jay Elms, MD;
Richard Cohen, PhD;
Martin G. White, MD
Arch Intern Med. 1976;136(10):1131-1134.
Abstract
Five patients on chronic hemodialysis regimens were hospitalized with six episodes of Staphylococcus aureus septicemia. Three of the patients acquired the infection during home dialysis, and it was related to the hemodialysis circulatoryaccess site in four. Initial therapy was methicillin sodium. Vancomycin hydrochloride was given in a 1-gm, single, weekly dose as the sole antibiotic after a short interval (mean, three days). Five of the six episodes were treated successfully. Staphylococcus epidermidis grew in blood cultures obtained during one of the treatments. The advantages of this regimen included a more prompt ambulation and the discontinuation of constant infusions in patients with no peripheral veins available.
(Arch Intern Med 136:1131-1134, 1976)
Author Affiliations
From the Department of Medicine, University of Texas Southwestern Medical School, Dallas, and the Veterans Administration Hospital, Dallas. Dr Barcenas is now with St Luke's Episcopal Hospital, Dallas.
Footnotes
Received for publication Oct 10, 1975; accepted March 12, 1976.
Reprint requests to Nephrology Section, St Luke's Episcopal Hospital, Texas Medical Center, Houston, TX 77025 (Dr Barcenas).
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