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Distressing Side-Effects of Minocycline Hydrochloride
W. Lee Fanning, MD;
Dieter W. Gump, MD
Arch Intern Med. 1976;136(7):761-762.
Abstract
Minocycline hydrochloride is a tetracycline derivative that has been advocated as the drug of choice in the treatment of meningococcal carriers. Recently, we studied a group of 30 patients who experienced a large number of sideeffects after receiving minocycline for treatment of meningococcal meningitis. Twenty-seven of 30 (90%) suffered from dizziness, vertigo, ataxia, weakness, nausea, and vomiting. These symptoms appeared within the first 72 hours of taking minocycline, and disappeared within 48 hours of stopping the medication.
(Arch Intern Med 136:761-762, 1976)
Author Affiliations
From the Department of Medicine, University of Vermont College of Medicine, Burlington.
Footnotes
Received for publication June 13, 1975; accepted Oct 11.
Reprint requests to Infectious Disease Unit, Department of Medicine, Given Building C315, University of Vermont College of Medicine, Burlington, VT 05401 (Dr Fanning).
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