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Malaria Complicating Neoplastic Disease
Michael L. Tapper, MD;
Donald Armstrong, MD
Arch Intern Med. 1976;136(7):807-810.
Abstract
Two patients with neoplastic disease had transfusion-induced malaria. In a patient with acute myelogenous leukemia infected with Plasmodium vivax, neither his underlying disease nor intensive cytotoxic chemotherapy appeared to ameliorate or worsen the clinical course of his infection. In a splenectomized patient with metastatic carcinoma of the colon, P malariae infection was associated with a fulminant course simulating cerebral malaria. Despite delay in diagnosis, both patients responded dramatically to antimalarial chemotherapy and both developed appreciable antibody responses.
(Arch Intern Med 136:807-810, 1976)
Author Affiliations
From the Infectious Disease Sevice, Department of Medicine, Memorial Sloan-Kettering Cancer Center, and Cornell University Medical College, New York.
Footnotes
Received for publication Aug 1, 1975; accepted Jan 6, 1976.
Reprint requests to Memorial Hospital, 1275 York Ave, New York, NY 10021 (Dr Armstrong).
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