This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Lincoln J. Bynum, MD; Robert W. Parkey, MD; James E. Wilson III, MD

Arch Intern Med. 1977;137(10):1385-1389.

Abstract
Fibrinogen/fibrin degradation products (FDP/fdp) and soluble fibrin complexes (SFC) were measured serially in 60 patients heparinized for pulmonary embolism or deep venous thrombosis. Eight patients had recurrent thromboembolism. In patients without recurrence, FDP/fdp and SFC tended to normalize within three to five days. In patients with recurrence, results of both tests were significantly higher on admission, and FDP/fdp values were significantly higher throughout ten days of therapy, than in patients without recurrence. The SFC values were not different between the two groups during the first six days of treatment, but again became significantly higher on the seventh day in patients with recurrence. There were no differences in clotting times, heparin dosage, or any other clinical features between patients with and without recurrence. Measurement of FDP/fdp and SFC can help identify patients at risk of recurrent thromboembolism if performed serially during treatment.

(Arch Intern Med 137:1385-1389, 1977)

Author Affiliations
From the Departments of Internal Medicine (Drs Bynum and Wilson) and Nuclear Medicine (Dr Parkey), University of Texas Health Science Center at Dallas.

Footnotes
Accepted for publication Nov 29, 1976.

Reprint requests to Pulmonary H8.116, 5323 Harry Hines Blvd, Dallas, TX 75235 (Dr Bynum).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Recurrent Leg Symptoms Following Deep Vein Thrombosis: A Diagnostic Challenge
Leclerc et al.
Arch Intern Med 1985;145:1867-1869.
ABSTRACT  

Fibrin Degradation Products and Impedance Plethysmography
Foti and Gurewich
Arch Intern Med 1980;140:903-906.
ABSTRACT  

Diagnostic Value of Tests of Fibrin Metabolism in Patients Predisposed to Pulmonary Embolism
Bynum et al.
Arch Intern Med 1979;139:283-285.
ABSTRACT