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Circulating Anticoagulant in the Procainamide-Induced Lupus Syndrome
William R. Bell, MD;
Gerry R. Boss, MD;
John S. Wolfson, PhD, MD
Arch Intern Med. 1977;137(10):1471-1473.
Abstract
An elderly man with procainamide hydrochloride-induced lupus syndrome had a circulating anticoagulant against factor XI and a biologic false-positive (BFP) test result for syphilis. This was not associated with hemorrhagic problems. The activity of the circulating anticoagulant and the BFP disappeared within days following discontinuation of procainamide and the administration of corticosteroids.
(Arch Intern Med 137:1471-1473, 1977)
Author Affiliations
From the Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine and Hospital, Baltimore. Dr Boss is now with the Bureau of Medical Sciences, Public Health Service, San Diego. Dr Wolfson is with the Department of Medicine, Massachusetts General Hospital, Boston.
Footnotes
Accepted for publication Oct 29, 1976.
Reprint requests to Johns Hopkins University-Hospital, Hematology Division, Blalock 1002, 601 N Broadway, Baltimore, MD 21205 (Dr Bell).
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