This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (29)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Diagnosis and Assessment of Extent of Involvement by Radioisotope Studies

Harry Carloss, MD; David Winslow, MD; Louis Kastan, MD; Lung T. Yam, MD

Arch Intern Med. 1977;137(7):863-866.

Abstract
In two patients with extensive marrow necrosis, the diagnosis of marrow necrosis was established by morphologic and radioisotopic studies, and the extent of involvement was accurately assessed by marrow scanning with technetium Tc 99m sulfur colloid while the patients were still alive. The literature on marrow necrosis was briefly reviewed and the clinical features of this condition were characterized. It was found that patients with this condition often have malignancies, underlying marrow disorders, sepsis, bone pain, and pancytopenia. Their marrow is often difficult to aspirate and they may require frequent transfusions to maintain a stable hemoglobin level. Radioisotopic studies are useful in the diagnosis and assessment of extent of involvement of this condition. They should be used in patients with clinical findings suggestive of marrow necrosis.

(Arch Intern Med 137:863-866, 1977)

Author Affiliations
From the Divisions of Hematology-Oncology and Diagnostic Radiology, Veterans Administration Hospital; Departments of Medicine and Diagnostic Radiology, University of Louisville, Louisville, Ky.

Footnotes
Accepted for publication Oct 7, 1976.

Reprint requests to Veterans Administration Hospital, 800 Zorn Ave, Louisville, KY 40206 (Dr Carloss).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?