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Richard J. Warrington, MB, PhD, FRCP(C); Georgina R. Hogg, MD; Frixos Paraskevas, MD; Kam S. Tse, MD

Arch Intern Med. 1977;137(7):927-930.

Abstract
A patient who was receiving rifampin treatment for tuberculosis developed heterogenous light-chain proteinuria and insidious renal failure after a period of fluid restriction. The renal damage was characterized pathologically by an interstitial nephritis with invasive tubular casts and an associated renal vein thrombosis. The possible role of the light-chain proteinuria in the pathogenesis of the renal failure is discussed.

(Arch Intern Med 137:927-930, 1977)

Author Affiliations
From the Departments of Immunology and Medicine (Drs Warrington, Paraskevas, and Tse) and Pathology (Dr Hogg), Faculty of Medicine, University of Manitoba, and the Clinical Investigation Unit, Health Sciences Centre, Winnipeg, Manitoba.

Footnotes
Accepted for publication Sept 9, 1976.

Reprint requests to Section of Allergy and Clinical Immunology, Health Sciences Centre, 700 William Ave, Winnipeg, Manitoba, Canada R3E 0Z3 (Dr Warrington).

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