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Successful Outcome With Amphotericin B and Griseofulvin Therapy

John F. Brown, Jr, MD; Leon S. Gottlieb, MD; Ruth A. McCormick, MD

Arch Intern Med. 1977;137(7):936-938.

Abstract
An ominous prognosis is associated with combined pulmonary and rhinocerebral mucormycosis (phycomycosis). We report the case of a diabetic patient with ketoacidosis who had extensive pulmonary and rhinocerebral mucormycosis that responded satisfactorily to amphotericin B and griseofulvin therapy. The affected lung is completely atelectatic and has remained so for 12 months without evidence of necrosis or abscess formation.

(Arch Intern Med 137:936-938, 1977)

Author Affiliations
From the Pulmonary Service, Department of Medicine (Drs Brown and Gottlieb), and the Neurology Service (Dr McCormick), University of Southern California School of Medicine and the Los Angeles County—University of Southern California Medical Center.

Footnotes
Accepted for publication Sept 22, 1976.

Reprint requests to Pulmonary Service, LAC-USC Medical Center, 1200 N State St, Los Angeles, CA 90033 (Dr Brown).

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