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Response to Corticosteroids in the Hypereosinophilic SyndromeAssociation With Increased Serum IgE Levels
Robert K. Bush, MD;
Mario Geller, MD;
William W. Busse, MD;
Dennis K. Flaherty, PhD;
Helen A. Dickie, MD
Arch Intern Med. 1978;138(8):1244-1246.
Abstract
Severe blood eosinophilia (16,500/cu mm and 6,500/cu mm) accompanied by involvement of the lungs, pleura, heart, pericardium, liver, gastrointestinal tract, peripheral nerves, or skin developed in two patients with bronchial asthma. Associated with the eosinophilia were elevated serum IgE levels (1,400 IU/ml and 10,500 IU/ml), depressed serum C4 complement levels (13 mg/100 ml and 6 mg/100 ml), and high titers of rheumatoid factor (1:2560 and 1:640). Symptoms improved after treatment with prednisone and the eosinophil counts and serum IgE and C4 complement levels returned to normal.
(Arch Intern Med 138:1244-1246, 1978)
Author Affiliations
From the Sections of Allergy and Immunology (Drs Bush, Geller, and Busse), Chest Medicine (Dr Dickie), and the Department of Medicine and Preventive Medicine (Dr Flaherty), University of Wisconsin, Madison.
Footnotes
Accepted for publication Nov 7, 1977.
Reprint requests to 504 N Walnut St, Madison, WI 53706 (Dr Bush).
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