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Disseminated Cryptococcosis Presenting as Palpable Purpura
Mark H. Greene, MD;
Abe M. Macher, MD;
Alfred D. Hernandez, MD;
Kenneth J. Tomecki, MD;
Bruce Chabner, MD
Arch Intern Med. 1978;138(9):1412-1413.
Abstract
Disseminated cryptococcosis with palpable purpura as the initial clinical manifestation developed in a patient with diffuse histiocytic lymphoma. Cryptococcal vascular injury in a thrombocytopenic cancer patient best explains this previously unreported presentation of cryptococcosis. Purpuric presentations of disseminated fungal infection are likely to increase in frequency as cancer therapy becomes more aggressive.
(Arch Intern Med 138:1412-1413, 1978)
Author Affiliations
From the Environmental Epidemiology Branch (Dr Greene), Dermatology Branch (Drs Hernandez and Tomecki), and Medicine Branch (Dr Chabner), National Cancer Institute, and the Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases (Dr Macher), National Institutes of Health, Public Health Service, Department of Health, Education, and Welfare, Bethesda, Md.
Footnotes
Accepted for publication April 10, 1978.
Reprint requests to Environmental Epidemiology Branch, National Cancer Institute, Landow Building, Room 3C-18, Bethesda, MD 20014 (Dr Greene).
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