This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (5)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Report on Two Patients With Immunoglobulin Deficiency

Donal D. O'Sullivan, MD; Puthalath Raghuprasad, MD; Ediz Z. Ezdinli, MD

Arch Intern Med. 1979;139(10):1131-1134.

Abstract
Multiple epithelial malignant neoplasms developed in two patients with Hodgkin's disease subsequent to radiotherapy and intensive chemotherapy. At the time of diagnosis, each patient also demonstrated a serum immunoglobulin deficiency. The significance of the occurrence of solid tumors in patients following therapy for Hodgkin's disease and the significance of cellular and humoral immunodeficiency in Hodgkin's disease in relation to second cancer development were studied. We suggest the establishment of a registry of leukemias and solid tumors developing in patients treated for Hodgkin's disease and other malignant neoplasms, possibly with detailed recording of immunocompetence data.

(Arch Intern Med 139:1131-1134, 1979)

Author Affiliations
From the Division of Oncology/Hematology (Drs O'Sullivan and Ezdinli) and the Department of Medicine (Dr Raghuprasad), The Chicago Medical School, Chicago, and the Oncology Section, Veterans Administration Medical Center, North Chicago, Ill (Dr Ezdinli).

Footnotes
Accepted for publication March 19, 1979.

Reprint requests to Veterans Administration Medical Center, North Chicago, IL 60064 (Dr Ezdinli).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?