This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (18)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

D. Christopher Bosworth, MD

Arch Intern Med. 1979;139(7):823-824.

Abstract
A 13-year-old girl who had been well previously was admitted with fulminant meningococcemic purpura. Her plasma cortisol level was only 3 µg/dL and failed to rise after cosyntropin administration. Maintenance doses of corticosteroid were administered. As her infection cleared her adrenal glands were restimulated and shown to have near normal response. Replacement doses of corticosteroids should be given to patients with fulminant meningococcemia until adrenal cortical insufficiency can be excluded because of the high incidence of adrenal failure in these patients and the possibility that excessive adrenal stimulation might contribute to adrenal abnormality.

(Arch Intern Med 139:823-824, 1979)

Author Affiliations
From the Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.

Footnotes
Accepted for publication Feb 14, 1979.

Reprint requests to 321 Main St, Newport News, VA 23601 (Dr Bosworth).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Assessment of Adrenal Function in the Initial Phase of Meningococcal Disease
Bone et al.
Pediatrics 2002;110:563-569.
ABSTRACT | FULL TEXT  

Update on Meningococcal Disease with Emphasis on Pathogenesis and Clinical Management
van Deuren et al.
Clin. Microbiol. Rev. 2000;13:144-166.
ABSTRACT | FULL TEXT  

Acute Adrenal Insufficiency in Association With Pancreatic Carcinoma
Lardinois et al.
Arch Fam Med 1993;2:1194-1197.
ABSTRACT