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Cushing's DiseaseRecurrence After a Surgically Induced Remission
Allan Pont, MD;
Arthur Gutierrez-Hartman, MD
Arch Intern Med. 1979;139(8):938-940.
Abstract
In December 1976, an 18-year-old woman had symptoms typical of Cushing's syndrome. Laboratory evaluations and roentgenograms documented pituitary-dependent Cushing's disease in a patient with a pituitary microadenoma. In May 1977, she underwent transsphenoidal pituitary exploration. A 2-mm pituitary microadenoma was removed. The patient improved, and laboratory evaluation documented remission of the disease. In June 1978, she again complained of symptoms compatible with Cushing's disease. Laboratory evaluation confirmed a pituitary-dependent hypercortisonism. This case report marks the first recurrence of Cushing's disease in a patient previously cured by transsphenoidal resection of a pituitary tumor.
(Arch Intern Med 139:938-940, 1979)
Author Affiliations
From the Departments of Medicine, Santa Clara Valley Medical Center, San Jose, Calif (Dr Pont) and Stanford (Calif) University Medical Center (Dr Gutierrez-Hartman).
Footnotes
Accepted for publication March 7, 1979.
Reprint requests to Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128 (Dr Pont).
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