 |
|
Glucocorticoid Effects in Vitamin D Intoxication
William F. Streck, MD;
Christine Waterhouse, MD;
John G. Haddad, MD
Arch Intern Med. 1979;139(9):974-977.
Abstract
Calcium balance studies and measurement of 25-hydroxyvitamin D (25[OH]D 3) levels were performed on a vitamin D intoxicated, hypoparathyroid patient before, during, and after successful management of hypercalcemia with oral prednisone therapy. Prednisone effected a dramatic reduction in both mean serum calcium levels and mean 24-hour urinary calcium excretion within four days on two separate occasions. No changes were apparent in fecal calcium excretion. Calcium balance became less negative with prednisone treatment. Levels of 25(OH) D during the same period did not change. Decreased calcium mobilization from bone best accounted for the glucocorticoid-mediated amelioration of hypercalcemia.
(Arch Intern Med 139:974-977, 1979)
Author Affiliations
From the Division of Endocrinology and Metabolism, University of Rochester (New York) School of Medicine and Dentistry (Drs Streck and Waterhouse), and the Division of Endocrinology, The Jewish Hospital of St Louis (Dr Haddad).
Footnotes
Accepted for publication March 19, 1979.
Reprint requests to University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642 (Dr Waterhouse).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety
Vieth
Am J Clin Nutr 1999;69:842-856.
ABSTRACT
| FULL TEXT
|
