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A Clinical, Epidemiologic, Serologic, and Virologic Study of Influenza C Virus Infection
Aubert C. Dykes, MD;
James D. Cherry, MD;
Carolyn E. Nolan, MPH
Arch Intern Med. 1980;140(10):1295-1298.
Abstract
• During a study of influenza-like illness in employees in the Pediatric Clinic at UCLA Hospital and Clinics in late November 1978, an influenza C viral strain was recovered from one employee, one person had more than a fourfold hemagglutination inhibition antibody titer rise to influenza C, and one person had specific influenza C IgM antibody. A survey of 334 children and young adults noted a seropositivity rate to influenza C of 64% for children up to 5 years old; 96% for 6- to 10-year-olds; 100% for 11- to 15-year-olds; and 98% for those over 16 years old. The 64% seropositivity of those children 5 years old and younger indicates that infection with influenza C early in life is common. The increasing seropositivity rates with age suggest that circulation and reinfection with influenza C commonly occurs.
(Arch Intern Med 140:1295-1298, 1980)
Author Affiliations
From the Department of Pediatrics, Center for the Health Sciences, UCLA School of Medicine, Los Angeles.
Footnotes
Accepted for publication Sept 18, 1979.
Reprint requests to Department of Pediatrics, Center for the Health Sciences, UCLA School of Medicine, Los Angeles, CA 90024 (Dr Cherry).
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