Lymphocytic Thyroiditis With Spontaneously Resolving Hyperthyroidism (Silent Thyroiditis)

doi:10.1001/archinte.1980.00330160038023

You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.

Vol. 140 No. 4, April 1980

Online Only
	•	Online First Table of Contents

ORIGINAL INVESTIGATIONS

•	Online Features

This Article
•	References
•	Full text PDF
•	Reply to article
•	Send to a friend
•	Save in My Folder
•	Save to citation manager
•	Permissions

Citing Articles
•	Citation map
•	Citing articles on HighWire
•	Citing articles on Web of Science (129)
•	Contact me when this article is cited

Related Content
•	Similar articles in this journal

Social Bookmarking
	What's this?

Lymphocytic Thyroiditis With Spontaneously Resolving Hyperthyroidism (Silent Thyroiditis)

Thomas F. Nikolai, MD; James Brosseau, MD; Mary Alice Kettrick, PhD; Ronald Roberts, PhD; Efstathios Beltaos, MD

Arch Intern Med. 1980;140(4):478-482.

Abstract

• Spontaneously resolving hyperthyroidism (SRH) is a transientform of hyperthyroidism characterized by a painless, nontender,normal-sized or slightly enlarged thyroid gland, elevated levelsof thyroxine and triiodothyronine, a depressed thyroid radioactiveiodine uptake (RAIU), spontaneous resolution in two to fivemonths, and a focal or diffuse lymphocytic thyroiditis on biopsy.Since 1962,62 episodes of SRH were found in 56 individuals.Twelve thyroid biopsy specimens showed diffuse or focal lymphocyticthyroiditis. Testing of viral antibodies to a wide range ofviruses demonstrated only one patient with notable titer changeof 18 tested. Resolution of the hyperthyroidism took two tofive months. Four patients were treated inappropriately. Lymphocyticthyroiditis with spontaneously resolving hyperthyroidism appearsto be a new syndrome that has dramatically increased in frequencyin the past ten years. It is difficult to differentiate fromcommon forms of hyperthyroidism unless RAIU is determined.

(Arch Intern Med 140:478-482, 1980)

Author Affiliations

From the Marshfield Clinic and Marshfield Medical Foundation, Marshfield, Wis.

Footnotes

Accepted for publication July 10, 1979.

Reprint requests to Marshfield Clinic, 1000 N Oak Ave, Marshfield,WI 54449 (Dr Nikolai).

Add to CiteULike CiteULike Add to Connotea Connotea Add to Delicious Delicious Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Uncommon Causes of Thyrotoxicosis
Mittra et al.
JNM 2008;49:265-278.
ABSTRACT | FULL TEXT

Scintigraphic Manifestations of Thyrotoxicosis
Intenzo et al.
RadioGraphics 2003;23:857-869.
ABSTRACT | FULL TEXT

Incomplete Thyrotroph Suppression Determined by Third Generation Thyrotropin Assay in Subacute Thyroiditis Compared to Silent Thyroiditis or Hyperthyroid Graves' Disease
Ito et al.
J. Clin. Endocrinol. Metab. 1997;82:616-619.
ABSTRACT | FULL TEXT

Ipodate Therapy in Patients With Severe Destruction-Induced Thyrotoxicosis
Arem and Munipalli
Arch Intern Med 1996;156:1752-1757.
ABSTRACT

Outcome of Hypothyroidism Caused by Hashimoto's Thyroiditis
Comtois et al.
Arch Intern Med 1995;155:1404-1408.
ABSTRACT

Clinical Course of Silent Thyroiditis in a Patient With Sjogren's Syndrome: Concomitant Changes of Antithyroid Antibodies and Antinuclear Antibody
Mitani et al.
Arch Intern Med 1988;148:1974-1975.
ABSTRACT

Postpartum Lymphocytic Thyroiditis: Prevalence, Clinical Course, and Long-term Follow-up
Nikolai et al.
Arch Intern Med 1987;147:221-224.
ABSTRACT

Elevation of Anti-DNA Antibody Titer During Thyrotoxic Phase of Silent Thyroiditis
Tajiri et al.
Arch Intern Med 1986;146:1623-1624.
ABSTRACT

Hypersensitivity Caused by Synthetic Thyroid Hormones in a Hypothyroid Patient With Hashimoto's Thyroiditis
Shibata et al.
Arch Intern Med 1986;146:1624-1625.
ABSTRACT

Silent Thyroiditis
Tajiri et al.
Arch Intern Med 1986;146:1644-1644.
ABSTRACT

Postpartum Thyroid Dysfunction
Goldman
Arch Intern Med 1986;146:1296-1299.
ABSTRACT

Incidence of Thyroid Dysfunction in an Unselected Postpartum Population
Freeman et al.
Arch Intern Med 1986;146:1361-1364.
ABSTRACT

The Various Presentations of Thyroiditis: Diagnostic Considerations
HAMBURGER
ANN INTERN MED 1986;104:219-224.
ABSTRACT

Euthyroid Atypical Subacute Thyroiditis Simulating Systemic or Malignant Disease
Rotenberg et al.
Arch Intern Med 1986;146:105-107.
ABSTRACT

Thyrotoxic Silent Thyroiditis: A Geographic Puzzle
Ureles and Cronmiller
Arch Intern Med 1985;145:2263-2263.
ABSTRACT

Thyrotoxic Silent Thyroiditis: A Geographic Puzzle-Reply
Goldman
Arch Intern Med 1985;145:2263-2264.
ABSTRACT

Frequency of Silent Thyroiditis
Schneeberg
Arch Intern Med 1985;145:2268-2268.
ABSTRACT

Frequency of Silent Thyroiditis-Reply
Nikolai
Arch Intern Med 1985;145:2268-2270.
ABSTRACT

Hyperthyroidism After Primary Hypothyroidism: Follow-up With Serial Thyroid Biopsies
Wakakuri et al.
Arch Intern Med 1985;145:1527-1528.
ABSTRACT

Silent (Painless) Thyroiditis: Evidence of a Geographic Variation in Frequency
Vitug and Goldman
Arch Intern Med 1985;145:473-475.
ABSTRACT

Current Concepts of Thyroiditis
Levine
Arch Intern Med 1983;143:1952-1956.
ABSTRACT

Recurrence and Heterogeneity in Painless Thyrotoxic Lymphocytic Thyroiditis: Report of Five Cases
Taylor and Sheeler
JAMA 1982;248:1085-1088.
ABSTRACT

Silent Thyrotoxic Thyroiditis
KLEIN and Levey
ANN INTERN MED 1982;96:242-244.
ABSTRACT

Lymphocytic Thyroiditis With Spontaneously Resolving Hyperthyroidism and Subacute Thyroiditis: Long-term Follow-up
Nikolai et al.
Arch Intern Med 1981;141:1455-1458.
ABSTRACT

| | |