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SarcoidosisRetroperitoneal Fibrosis, Renal Arterial Involvement, and Unilateral Focal Glomerulosclerosis
Michel Godin, MD;
Jean-Paul Fillastre, MD;
Thierry Ducastelle, MD;
Jacques Hemet, MD;
Pierre Morere, MD;
George Nouvet, MD
Arch Intern Med. 1980;140(9):1240-1242.
Abstract
• In one patient with pulmonary sarcoidosis, hypertension occurred during the course of the disease. Aortography showed extensive narrowing of the right renal artery. Surgical exploration disclosed extensive periaortic and perirenal fibrosis. This fibrosis encircled the right renal artery and caused extrinsic compression. Pathological examination disclosed a large amount of histiocyte epithelioid infiltration in various samples of the fibrosis and particularly in the adventitia of the renal artery, highly suggestive of sarcoidal angiitis. Surgical biopsy was performed on both kidneys. The right kidney, protected by arterial stenosis, was little altered, while the left kidney showed extensive interstitial, tubular, and glomerular lesions. The glomerular lesions were focal and segmental hyalinosis.
(Arch Intern Med 140:1240-1242, 1980)
Author Affiliations
From the Renal Unit (Drs Godin and Fillastre), Pathology Department (Drs Ducastelle and Hemet), and Pneumology Unit (Drs Morere and Nouvet), Hôpitaux de Rouen, Rouen, France.
Footnotes
Accepted for publication Dec 10, 1979.
Reprint requests to Renal Unit, Hôpital de Bois-Guillaume, 76230 Bois Guillaume, France (Dr Godin).
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