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Sickle Cell Trait and Glucose-6-Phosphate Dehydrogenase DeficiencyEffects on Health and Military Performance in Black Navy Enlistees
Anne Hoiberg, MS;
John Ernst, MA;
CDR David E. Uddin, MC, USN
Arch Intern Med. 1981;141(11):1485-1488.
Abstract
The purpose of this longitudinal study was to compare the Navy performance and health status during a four-year enlistment of four subsamples of black enlistees who began active service between Feb 14 through Sept 15, 1972. On the basis of results obtained from screening procedures for hemoglobinopathies, a sample of 8,725 enlistees was separated into four subgroups: 599 subjects with sickle cell trait, 1,003 subjects with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, 73 subjects with both trait anomalies, and 7,050 normal subjects. Results of comparative analyses indicated that the three trait subsamples did not differ significantly from the normal group on demographic and service-related variables, seven performance criteria, hospitalization rates, or mortality. Thus, the trait anomalies studied were found to be benign under routine conditions of naval service.
(Arch Intern Med 1981;141:1485-1488)
Author Affiliations
From the Environmental Medicine Department, Naval Health Research Center, San Diego (Ms Hoiberg); the University of Montana, Missoula (Mr Ernst); and the Naval Medical Research and Development Command, Bethesda, Md (Dr Uddin).
Footnotes
Accepted for publication Oct 9, 1980.
The views presented in this article are those of the authors. No endorsement by the Department of the Navy has been given or should be inferred.
Reprint requests to Naval Health Research Center, PO Box 85122, San Diego, CA 92138 (Ms Hoiberg).
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