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A Cautionary Note

Shantha Madhavan, MS; Michael H. Alderman, MD

Arch Intern Med. 1981;141(12):1583-1586.

Abstract
• The risk of cardiovascular disease (CVD) at various levels of systolic blood pressure (BP) and the potential benefit of BP reduction have been estimated by constructing probability tables for extended periods based on the Framingham Study data. These estimates demonstrate that systolic BP alone delineates subgroups of persons with widely divergent risk of CVD, depending both on their demographic and clinical characteristics. For example, the disparity in prognosis is such that some persons with a systolic BP of 160 mm Hg are at greater risk of subsequent CVD than others with a systolic BP of 195 mm Hg. The potential benefit to be derived from systolic BP reduction shows similarly wide variation, so initial pressure alone does not precisely predict the gain that might accompany BP reduction. Measures of greater prognostic value are needed to enhance the value of BP determination.

(Arch Intern Med 1981;141:1583-1586)

Author Affiliations
From the Department of Public Health, Cornell University Medical College, New York.

Footnotes
Accepted for publication Nov 20, 1980.

Read in part before the 52nd scientific sessions of the American Heart Association, Anaheim, Calif, Nov 13, 1979.

Reprints not available.

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