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Propranolol IntoxicationA Severe Case Responding to Norepinephrine Therapy
LCDR Thomas J. Halloran, MC, USNR;
LCDR Charles E. Phillips, MC, USNR
Arch Intern Med. 1981;141(6):810-811.
Abstract
• A patient with serious propranolol hydrochloride intoxication had seizures, hypotension, and was in a coma. Large amounts of propranolol were found in her serum and urine. Isoproterenol hydrochloride, a specific β-receptor agonist, was not effective in therapy. Hemodynamic improvement occurred with norepinephrine bitartrate. The half-life of propranolol was prolonged. She fully recovered.
(Arch Intern Med 1981;141:810-811)
Author Affiliations
From the Naval Regional Medical Center, Portsmouth, Va.
Footnotes
Accepted for publication May 27, 1980.
The views expressed herein are those of the authors and do not necessarily reflect the views of the Department of the Navy or the Department of Defense.
Reprint requests to US Naval Regional Medical Center, Box 7623, FPO San Francisco, CA 96630 (Dr Halloran).
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