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Ronald Pies, MD

Arch Intern Med. 1981;141(8):1087.

Abstract

• A 28-year-old woman received a single course of corticosteroids for treatment of ulcerative colitis. She subsequently became depressed; shortly thereafter, signs of mania developed. Despite discontinuation of corticosteroid therapy, the patient has had five bouts of mania, closely followed by severe depression, in the past 1 years. This seems to be the first case of persistent bipolar illness after exogenous steroid administration.

(Arch Intern Med 1981;141:1087)

Author Affiliations

Footnotes

Reprint requests to Department of Psychiatry, State University of New York Upstate Medical Center, 750 E Adams St, Syracuse, NY 13210 (Dr Pies).

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