This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Brent R. Gooch, MD; William L. Isley, MD; Robert D. Utiger, MD

Arch Intern Med. 1982;142(10):1801-1805.

Abstract
• Serum thyroid hormone, thyrotropin (TSH) and thyroxinebinding globulin (TBG) concentrations, free thyroxine index values, and free thyroxine concentrations were measured at the time of admission in all 77 patients hospitalized on a medical service on four separate days. Serum thyroxine (T₄) concentrations and serum free T₄ index values were decreased in 19.5% and 11.7%, respectively, and increased in 3.9% and 11.7%, respectively; serum free T₄ concentrations were decreased in 6.8% and increased in 5.4%. Six patients (7.8%) had increased serum TSH concentrations. Serum triiodothyronine (T₃) concentrations were decreased in 26.0% and reverse triiodothyronine (rT₃) concentrations were increased in 29.9%. None had manifestations of thyroid disease. These results indicate that available thyroid function tests may give misleading results in patients with nonthyrold illness and suggest that caution be exercised in diagnosing thyroid disease in hospitalized patients.

(Arch Intern Med 1982;142:1801-1805)

Author Affiliations
From the Department of Medicine, University of North Carolina School of Medicine, Chapel Hill. Dr Gooch's present affiliation is the Department of Medicine, Vanderbilt University, Nashville, Tenn.

Footnotes
Accepted for publication June 1,1982.

Reprint requests to Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27514 (Dr Utiger).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Hypothyroidism and Failure To Wean in Patients Receiving Prolonged Mechanical Ventilation at a Regional Weaning Center
Datta and Scalise
Chest 2004;126:1307-1312.
ABSTRACT | FULL TEXT  

Effect of Rifampin Therapy on Thyroid Function Tests in a Hypothyroid Patient on Replacement L-Thyroxine
ISLEY
ANN INTERN MED 1987;107:517-518.
ABSTRACT  

Hypothyroxinemia in Cardiac Arrest
Wortsman et al.
Arch Intern Med 1987;147:245-248.
ABSTRACT