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Left Atrial LeiomyosarcomaManifestation as Unexplained Pulmonary Vascular Disease
Virginia M. Donovan, MD;
Warren Summer, MD;
Grover M. Hutchins, MD
Arch Intern Med. 1982;142(10):1923-1925.
Abstract
• Primary, left-sided cardiac tumors are a rare cause of unexplained pulmonary hypertension. We describe herein two patients with leiomyosarcoma of the left atrium, who were Initially seen with symptoms suggestive of primary pulmonary hypertension, venoocclusive disease, or multiple, small thromboemboli. Postmortem examination showed extension of the leiomyosarcoma into the pulmonary veins, which resulted in pulmonary venous hypertension. Although unusual, the occurrence of left-sided cardiac neoplasms should be included in the differential diagnosis of patients who are initially seen with unexplained pulmonary hypertension. An open lung biopsy should be considered and may indicate a venous origin for the hypertension.
(Arch Intern Med 1982;142:1923-1925)
Author Affiliations
From the Department of Pathology (Drs Donovan and Hutchins) and the Respiratory Division of the Department of Medicine (Dr Summer), The Johns Hopkins Hospital, Baltimore.
Footnotes
Accepted for publication May 24, 1982.
Reprint requests to Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21205 (Dr Hutchins).
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