Staphylococcal Bacteremia and Endocarditis: State of the Art

doi:10.1001/archinte.1982.00340190125020

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Vol. 142 No. 6, June 1982

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Staphylococcal Bacteremia and Endocarditis

State of the Art

Arnold S. Bayer, MD

Arch Intern Med. 1982;142(6):1169-1177.

Abstract

• The major clinical difficulties in bacteremic Staphylococcusaureus infections involve the following: (1) differentiationof infective endocarditis (IE) from non-IE staphylococcemiasand (2) questions concerning optimum chemotherapy of deep-seatedstaphylococcemic infections. In this article, an algorithmicapproach to the differentiation of S aureus IE from non-IE staphylococcemiaswill be developed, particularly in regard to specific clinical,echocardiographic, radioisotopic, and serological "markers"for recognizing patients as at "high risk" for underlying Saureus IE. Also, data will be presented relating to the controversiesof monotherapy v combination chemotherapy in S aureus IE aswell as in bacteremic S aureus infections caused by antibiotic-tolerantS aureus strains.

(Arch Intern Med 1982;142:1169-1177)

Author Affiliations

From the Division of Infectious Disease, Harbor-UCLA Medical Center, Torrance, Calif.

Footnotes

Accepted for publication Jan 11, 1982.

Reprinted with permission from the Bulletin of the AmericanCollege of Chest Physicians (1980;3:8-19).

Reprint requests to Division of Infectious Diseases, Harbor-UCLAMedical Center, 1000 Carson St, Torrance, CA 90509 (Dr Bayer).

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