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Donald A. Weiner, MD

Arch Intern Med. 1983;143(10):1978-1980.

Abstract
• To evaluate the conditions of patients with congestive heart failure and to follow up their response to therapy, Investigators have used standard clinical classification systems and roentgenographic, ultrasonic, and scintigraphic evaluations of left ventricular function and volumes. While useful in the initial characterization of the patient's condition, many of these measurements are imprecise or detect only small changes after therapy. The functional capacity or cardiac reserve is best evaluated by measuring maximal oxygen consumption during a standard exercise protocol. Potential limitations of exercise testing in following up therapy include the effects of placebo, training, and posture, and the choice of submaximal or maximal testing. The efficacy of investigational inotropic or vasodilator therapy on the patient's central or peripheral circulations should also be measured by hemodynamic monitoring at rest and during exercise to determine the optimal therapy for a particular patient with heart failure.

(Arch Intern Med 1983;143:1978-1980)

Author Affiliations
From the Evans Memorial Department of Clinical Research and the Department of Medicine, University Hospital, Boston University Medical Center.

Footnotes
Accepted for publication May 2,1983.

Read in part before the 14th annual Cardiovascular Conference, Snowmass, Colo, Jan 20,1983.

Reprint requests to the Department of Cardiology, University Hospital, 75 E Newton St, Boston, MA 02118 (Dr Weiner).

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