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  Vol. 143 No. 2, February 1983 TABLE OF CONTENTS
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Nontuberculous Mycobacterial Disease

Experience in a Southern California Hospital

Geoffrey J. Gorse, MD; Ronald D. Fairshter, MD; Gary Friedly; Luis Dela Maza, MD; Gerald R. Greene, MD; Thomas C. Cesario, MD

Arch Intern Med. 1983;143(2):225-228.


Abstract

• The experience with nontuberculous mycobacterial disease at an "acute-care" hospital in southern California between 1971 and 1981 is reported. Forty-five patients with nontuberculous mycobacterial or Mycobacterium bovis— caused disease were identified by retrospective review. Of these, 31 patients (69%) had pulmonary infection alone, nine (20%) had cervical lymphadenitis, two (4%) had disseminated disease, two (4%) had cutaneous infection, and one had soft tissue infection. Nonmycobacterial pulmonary disease was noted in 15 (33%) of the patients and underlying malignant neoplasms were noted in eight (18%). Symptoms most frequently reported at initial examinations of patients with pulmonary disease were cough, weight loss, sputum production, and fatigue. Response to therapy was more successful in patients with Mycobacterium kansasii—caused disease than in those with Mycobacterium avium-intracellulare—caused pulmonary disease. We conclude that nontuberculous mycobacterial disease is not rare in the general hospital setting in southern California.

(Arch Intern Med 1983;143:225-228)



Author Affiliations

From the Divisions of Infectious Diseases (Drs Gorse and Cesario) and Pulmonary and Critical Care Medicine (Dr Fairshter), and the Departments of Pathology (Mr Friedly and Dr Dela Maza) and Pediatrics (Dr Greene), University of California, Irvine Medical Center, Orange.


Footnotes

Accepted for publication Aug 23, 1982.

Reprint requests to the Division of Infectious Diseases, Department of Medicine, University of California, Irvine Medical Center, 101 City Dr S, Orange, CA 92668 (Dr Gorse).



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