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Thomas J. Marrie, MD; J. William Costerton, MD

Arch Intern Med. 1983;143(6):1135-1141.

Abstract
• In this study we have shown extensive microbial colonization of the surface of urine droppers and urine collecting systems from bacteriuric patients. In all instances there was an extensive background matrix and fibrous strands interconnected the bacteria. A "slime" layer completely encased bacteria on occasion. These observations suggest that incorporation of blockers of bacterial adhesion into the surfaces of these devices should be explored as one method of delaying, or in some cases preventing, catheter-acquired bacteriuria.

(Arch Intern Med 1983;143:1135-1141)

Author Affiliations
From the Departments of Medicine and Microbiology, Dalhousie University and the Victoria General Hospital, Halifax, Nova Scotia (Dr Marrie); and the Department of Biology, the University of Calgary, Alberta (Dr Costerton).

Footnotes
Accepted for publication Feb 1, 1983.

Reprint requests to Department of Microbiology, 5788 University Ave, Halifax B3H 1V8, Nova Scotia, Canada (Dr Marrie).

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