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Acute Nonlymphocytic Leukemia and Acute Aplastic AnemiaThe Simultaneous Occurrence in Marital Partners
F. Marc Stewart, MD;
Charles E. Hess, MD
Arch Intern Med. 1983;143(6):1156-1158.
Abstract
• A young husband and wife couple presented simultaneously with aplastic anemia and acute myelomonocytic leukemia, respectively. No etiologic agent or exposure was identified. With appropriate therapy, the wife achieved a complete remission and the husband has had a good response. Potential etiologic environmental factors known to cause both disorders are discussed. A single causative agent may induce stem-cell changes in genetically dissimilar persons and produce a spectrum of pathologic features ranging from aplastic anemia to acute leukemia.
(Arch Intern Med 1983;143:1156-1158)
Author Affiliations
From the Division of Hematology-Oncology, the Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville.
Footnotes
Accepted for publication Jan 7, 1983.
Reprint requests to Box 502, University of Virginia Hospital, Charlottesville, VA 22908 (Dr Hess).
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