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Successful Removal After Hemostasis With Lyophilized Cryoprecipitate

Michael Small, MB, MRCP; Gordon D. O. Lowe, MB, MRCP; Ken Davidson, MB, FRCS; Charles D. Forbes, MD, FRCP; Colin R. M. Prentice, MD, FRCP

Arch Intern Med. 1983;143(8):1604-1605.

Abstract
• A man with severe von Willebrand's disease who had hemoptysis was followed-up for 2 years for continued hemoptysis and was discovered to have a bronchial carcinoma. Under close hematological surveillance, an uncomplicated pneumonectomy was performed, using a new factor VIII product— freeze-dried cryoprecipitate. This case illustrates that hemoptysis in von Willebrand's disease cannot always be attributed to the disease itself: that continued hemoptysis requires regular bronchoscopy and that major surgery can be performed in von Willebrand's disease with effective correction of the coagulation defect using freeze-dried cryoprecipitate.

(Arch Intern Med 1983;143:1604-1605)

Author Affiliations
From the Departments of Medicine (Drs Small, Lowe, Forbes, and Prentice) and Thoracic Surgery (Mr Davidson), Royal Infirmary, Glasgow, Scotland.

Footnotes
Accepted for publication Dec 17, 1982.

Reprint requests to the Department of Medicine, Royal Infirmary, Glasgow, Scotland G31 2ER (Dr Small).

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