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[ill]ulture-Negative' Prosthetic [ill]alve Endocarditis[ill]azards of Postoperative Steroid Therapy [ill]r Unexplained Fever
[ill]een Hilton, MD;
Chester W. Lerner, MD;
[ill]anklin D. Lowy, MD;
Michael L. Tapper, MD
Arch Intern Med. 1984;144(10):2083-2084.
Abstract
Two patients had prolonged unexplained fever along with [ill]tiple negative blood cultures after cardiac valve replace[ill]ent surgery. Following the administration of corticosteroids [ill] presumed postpericardiotomy syndrome, both patients [ill]proved symptomatically and defervesced, only to have [ill]sitive blood cultures for Staphylococcus epidermidis [ill]ortly thereafter. The theoretical and practical risks of the [ill]piric use of anti-inflammatory agents for unexplained post[ill]erative fever are reviewed. "Culture-negative" prosthetic [ill]vular infection due to prior antibiotic prophylaxis or therapy [ill]st be strongly considered in the evaluation of such unex[ill]ined fever.
(Arch Intern Med 1984;144:2083-2084)
Author Affiliations
[ill]rom the Division of Infectious Diseases, Department of Medicine, [ill]tefiore Medical Center, Bronx, New York (Drs Hilton and Lowy); and Section of Infectious Diseases, Department of Medicine, Lenox Hill [ill]pital, New York (Drs Lerner and Tapper).
Footnotes
[ill]ccepted for publication Nov 21, 1983.
[ill]eprint requests to the Section of Infectious Diseases, Lenox Hill [ill]pital, 100 E 77th St, New York, NY 10021 (Dr Tapper).
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