 |
|
Low Fractional Excretion of SodiumOccurrence With Hemoglobinuric- and Myoglobinuric-Induced Acute Renal Failure
Howard L. Corwin, MD;
Martin J. Schreiber, MD;
Leslie S. T. Fang, MD, PhD
Arch Intern Med. 1984;144(5):981-982.
Abstract
• Ten patients with myoglobinuric and hemoglobinuric acute renal failure demonstrated low fractional excretion of sodium (FENa) values (< 1%) during the oliguric phase of their course. Acute renal failure secondary to hemoglobinuria developed in five patients, and five demonstrated acute deterioration with myoglobinuria. The mean serum creatinine level increased from 1.1 mg/dL (range, 0.6 to 1.7 mg/dL) to a maximum of 6.9 mg/dL (range, 2 to 13.1 mg/dL). Although three patients required dialysis, all individuals eventually returned or were returning toward their baseline renal function at discharge. The importance of a low FENa in the setting of myoglobinuric and hemoglobinuric renal failure is reviewed. The findings in this report raise the possibility that a common mechanism may underlie the renal injury in both types of pigment toxicity.
(Arch Intern Med 1984;144:981-982)
Author Affiliations
From the Renal Unit and the Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston. Dr Corwin is now with Rush-Presbyterian-St Luke's Medical Center, Chicago; Dr Schreiber is now with the Cleveland Clinic Foundation.
Footnotes
Accepted for publication Sept 26, 1983.
Reprint requests to Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114 (Dr Fang).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Misapplications of Commonly Used Kidney Equations: Renal Physiology in Practice
Nguyen et al.
CJASN 2009;4:528-534.
ABSTRACT
| FULL TEXT
Can rhabdomyolysis be the only cause of acute renal failure in leptospirosis?
Liborio
Nephrol Dial Transplant 2005;20:2580-2581.
FULL TEXT
Renal Failure Secondary to Acute Tubular Necrosis: Epidemiology, Diagnosis, and Management
Gill et al.
Chest 2005;128:2847-2863.
ABSTRACT
| FULL TEXT
Diagnosis and Treatment of Acute Tubular Necrosis
Esson and Schrier
ANN INTERN MED 2002;137:744-752.
ABSTRACT
| FULL TEXT
Fractional Excretion of Sodium: Exceptions to Its Diagnostic Value
Zarich et al.
Arch Intern Med 1985;145:108-112.
ABSTRACT
|
