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A Study With Emphasis on the Elderly

Lawrence E. Klein, MD; Pearl S. German, ScD; David M. Levine, MD; E. Robert Feroli, Jr, PharmD; Joan Ardery

Arch Intern Med. 1984;144(6):1185-1188.

Abstract
• When patients ascribe adverse symptoms to their medications, the medical care process can be affected. To Investigate how often medical outpatients link various adverse symptoms with their medications and to learn what actions they take in response, 299 randomly selected medical outpatients were interviewed. Thirty percent of the subjects identified at least one medication as causing an undesirable symptom. Subjects 65 years or older attributed a lower mean number of adverse symptoms to their medications than did younger subjects. Subjects rarely reported modifying their medication regimens due to adverse symptoms, a finding supported by multiple regression analysis. Approximately one in four subjects did not discuss their symptoms with their providers. These results have important implications for medical care in general, and for the elderly in particular.

(Arch Intern Med 1984;144:1185-1188)

Author Affiliations
From the Department of Medicine (Drs Klein, Levine, and Feroli, and Ms Ardery), the Health Services Research and Development Center (Drs Klein, German, and Levine), and the Division of Health Education (Drs Klein, German, and Levine), The Johns Hopkins University, Baltimore.

Footnotes
Accepted for publication Dec 12,1983.

Read in part before the national meeting of the Gerontological Society of America, Boston, Nov 20,1982.

Reprint requests to Division of Internal Medicine, The Johns Hopkins Hospital, Harvey 502, 600 N Wolfe St, Baltimore, MD 21205 (Dr Klein).

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