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Hypercalcemia in the Neuroleptic Malignant Syndrome
Robert T. Wang, MD;
David E. Aftergood, MD;
Harold E. Carlson, MD
Arch Intern Med. 1985;145(1):143-144.
Abstract
The neuroleptic malignant syndrome (NMS) developed in a 32-year-old man following fluphenazine enanthate administration. Hypercalcemia was initially present, perhaps reflecting release of calcium from skeletal muscle stores. The elevated serum calcium levels support the existence of a peripheral muscle abnormality in the pathogenesis of the NMS and provides another point of similarity between NMS and malignant hyperthermia.
(Arch Intern Med 1985;145:143-144)
Author Affiliations
From the Medical and Research Services, Veterans Administration Wadsworth Medical Center; and the Department of Medicine, UCLA School of Medicine, Los Angeles. Dr Carlson is now with the Harry S Truman Memorial Veterans Hospital, Columbia, Mo.
Footnotes
Accepted for publication Feb 29, 1984.
Reprint requests to the Endocrinology Section, Harry S Truman Memorial Veterans Hospital, 800 Hospital Dr, Columbia, Mo 65201 (Dr Carlson).
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