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Quinidine-Induced Vasculitis
Meir Shalit, MD;
Moshe Y. Flugelman, MD;
Noam Harats, MD;
Eithan Galun, MD;
Zvi Ackerman, MD;
Juri Kopolovic, MD;
Marcel Eliakim, MD
Arch Intern Med. 1985;145(11):2051-2052.
Abstract
Four patients developed nonthrombocytopenic purpura two to three weeks after initiation of quinidine therapy. The skin lesions disappeared and did not recur after cessation of quinidine therapy. Histologic examination revealed leukocytoclastic vasculitis with deposition of C3, IgA, and/or IgM in the small dermal vessels. Since quinidine purpura is usually associated with thrombocytopenia, the possibility of leukocytoclastic vasculitis as an additional cause of purpura is stressed.
(Arch Intern Med 1985;145:2051-2052)
Author Affiliations
From the Departments of Medicine A (Drs Shalit, Flugelman, Harats, Galun, Ackerman, and Eliakim) and Pathology (Dr Kopolovic), Hadassah University Hospital, Jerusalem.
Footnotes
Accepted for publication Feb 8, 1985.
Reprint requests to Department of Medicine A, Hadassah University Hospital, PO Box 12000, Jerusalem 91120, Israel (Dr Shalit).
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