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Idiopathic Retroperitoneal Fibrosis and Primary Biliary CirrhosisA New Association?
François Sevenet, MD;
Dominique Capron-Chivrac, MD;
Richard Delcenserie, MD;
Christian Lelarge, MD;
Jacques Delamarre, MD;
Jean-Pierre Capron, MD
Arch Intern Med. 1985;145(11):2124-2125.
Abstract
We encountered a case of primary biliary cirrhosis in a nonalcoholic man who had been operated on for idiopathic retroperitoneal fibrosis 20 years previously. Chronic pancreatitis was also detected on endoscopic retrograde examination. After several episodes of digestive bleeding due to ruptured esophageal varixes, the patient died of massive hemorrhage. Postmortem examination showed stage 3 primary biliary cirrhosis and a thick retroperitoneal fibrous plaque, consisting of densely fibrotic areas of collagen with rare vessels and mononuclear cells. We suggest that idiopathic retroperitoneal fibrosis may be a new autoimmune disorder associated with primary biliary cirrhosis and that primary biliary cirrhosis is a potential cause of portal hypertension, cholestasis, or both in the course of idiopathic retroperitoneal fibrosis.
(Arch Intern Med 1985;145:2124-2125)
Author Affiliations
From the Hepatology and Gastroenterology Service (Drs Sevenet, Capron-Chivrac, Delcenserie, and Capron), the Pathology Service (Dr Lelarge), and the Radiology Service (Dr Delamarre), Centre Hospitalier Universitaire Nord, Amiens, France.
Footnotes
Accepted for publication May 28, 1985.
Reprint requests to the Clinique Médicale A, Centre Hospitalier Universitaire Nord, 80030 Amiens, France (Dr Capron).
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