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Cyclic Sinus Node Dysfunction in a Patient With Hyperthyroidism
Susumu Nakagawa, MD;
Akihiko Higa, MD;
Hiroyuki Kondoh, MD;
Yasushi Koiwaya, MD;
Kenjiro Tanaka, MD
Arch Intern Med. 1985;145(11):2126-2127.
Abstract
• In a 54-year-old woman with hyperthyroidism, episodic sinus node dysfunction (SND) recurred in a cyclic fashion. The SND occurred suddenly during normal sinus rhythm and progressed to marked sinus bradycardia; occasionally, sinus arrest developed with or without ventricular escape beats. A 1-mg dose of intravenous atropine sulfate suppressed the occurrence transiently. After a 200-mg dose of propylthiouracil and a 20-mg dose of prednisolone every six hours, the SND was completely abolished within 21 hours. It is probable that, together with a pathologic process induced by hyperthyroidism, the autonomic nervous system participated in our patient's episodic SND.
(Arch Intern Med 1985;145:2126-2127)
Author Affiliations
From the First Department of Internal Medicine, Miyazaki Medical College, Miyazaki, Japan.
Footnotes
Accepted for publication May 21, 1985.
Reprint requests to the First Department of Internal Medicine, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan (Dr Koiwaya).
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