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Ralph Carmel, MD

Arch Intern Med. 1985;145(3):484-485.

Abstract
• Pigmentation changes limited to skin appendages accompanied pernicious anemia in four patients. Two Latin-American patients, one with congenital and one with acquired pernicious anemia, had reddish hair while they were cobalamin deficient. With treatment, the new hair growth assumed its normal premorbid dark brown color. Two black patients with pernicious anemia had blue fingernails. The new nail growth after treatment was of normal color. Pigmentation changes seem to be more frequent in nonwhite than in white patients with cobalamin deficiency and may have various expressions.

(Arch Intern Med 1985;145:484-485)

Author Affiliations
From the Department of Medicine, University of Southern California and Los Angeles County-USC Medical Center.

Footnotes
Accepted for publication June 31, 1984.

Reprint requests to USC School of Medicine, Raulston 306, 2025 Zonal Ave, Los Angeles, CA 90033 (Dr Carmel).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Reversible Hyperpigmentation of Skin and Nails With White Hair due to Vitamin B12 Deficiency
Noppakun and Swasdikul
Arch Dermatol 1986;122:896-899.
ABSTRACT