This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (26)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Joseph M. DeVito, PharmD; Joseph F. John, Jr, MD

Arch Intern Med. 1985;145(6):1053-1056.

Abstract
• Cefotaxime sodium was assigned to the open formulary for 12 months and then was placed on formulary restriction to evaluate the restriction's effect on rate of use by services and appropriateness of use. Over 18 months, 187 cases (72 before and 115 after restriction) were reviewed. The majority of use (prerestriction and postrestriction) was in the medicine, pediatrics, and surgery services. The postrestriction usage rate for the three services increased significantly. Cefotaxime was used appropriately in 85% of cases during both periods and was not used prophylactically. Appropriateness of use was independent of formulary restriction. During both periods, approximately 76% of patients received cefotaxime for pneumonia, sepsis, meningitis, or immunosuppression. Of 205 infections, gram-negative bacilli accounted for over half of the pathogens isolated. Thus, formulary restriction was ineffective in reducing the rate of cefotaxime usage and had no effect on the appropriateness of usage.

(Arch Intern Med 1985;145:1053-1056)

Author Affiliations
From the Department of Pharmacy (Dr DeVito) and the Division of Infectious Diseases and Immunology (Dr John), Veterans Administration Medical Center and the Medical University of South Carolina, Charleston.

Footnotes
Accepted for publication Oct 17, 1984.

Reprint requests to Division of Infectious Diseases and Immunology, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC 29403 (Dr John).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Commonality of Risk Factors for Nosocomial Colonization and Infection with Antimicrobial-Resistant Staphylococcus aureus, Enterococcus, Gram-Negative Bacilli, Clostridium difficile, and Candida
Safdar and Maki
ANN INTERN MED 2002;136:834-844.
ABSTRACT | FULL TEXT  

The successful introduction of a programme to reduce the use of iv ciprofloxacin in hospital
Weller
J Antimicrob Chemother 2002;49:827-830.
ABSTRACT | FULL TEXT  

Use of Antimicrobial Agents in a University Teaching Hospital: Evolution of a Comprehensive Control Program
Hirschman et al.
Arch Intern Med 1988;148:2001-2007.
ABSTRACT